What is Postbiotic?
A preparation of inanimate microorganisms and/or their components that confers a health benefit on the host
The ISAPP (The International Scientific Association of Probiotics and Prebiotics) consensus definition and scope for postbiotics is “A preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. Effective postbiotics must contain inactivated microbial cells or cell components, with or without metabolites, that contribute to observed health benefits.
Nutrignomix™ postbiotic is a non-living composition of metabolites and functional compounds that have been shown in 100 over published research studies with 2 patents to support immune and gut health.
5G Biotics
Prebiotics
Fibers that feed good bacteria.
Antibiotics
Medicine or chemical that can destroy harmful bacteria in the body.
Probiotics
Live beneficial bacteria in your gut.
Parabiotics
Inactivated microbial cells of probiotics.
Postbiotics
Metabolites produced by good bacteria.
Essence of Postbiotics
- Extracellular & secreted proteins
- Exopolysaccharide
- Teichoic acids & others cell wall components
- Anti-oxidant activities
- Enzymes
- Vitamins B1, B9, B12 & K
- Bacteriocins
Benefits of Nutrignomix™ Postbiotics
Improves gut health by maintaining the balance of gut microflora.
Possesses anti-inflammatory properties which aids in cancer prevention, also helps with psoriasis and eczema skin problems.
Strengthens intestinal epithelial barrier that improves irritable bowel syndrome (IBS).
Are Postbiotics the New Alternative to Probiotics?
The benefits of postbiotics are not commonly known and are often confused to be either a replacement or substitute for probiotics. As a matter of fact, both work hand-in-hand to create a balanced gut microbiome for good gut health.
However, the benefits of postbiotics far outweighs the ones provided by probiotics especially when incorporated into products such as food supplements, health supplements, and even cosmetics products. Which includes the following:
- Deliver consistent results without the need for survival in the gut.
- Stable at room temperature for up to two years.
- Do not induce inflammatory responses.
- Retains 75% of healthy bacteria upon consumption, way above the 20% benchmark.
- Does not require refrigeration, easy for logistics and manufacturing purposes.
These are advantages associated when considering postbiotics as a probiotics substitute or replacement to support the overall health.
Differences between Probiotics and Postbiotics
| Probiotic | Postbiotic |
| Must survive before giving good effects. | Probiotic essence (safer because no living cells/microbes). |
| Inconsistent results. | Consistent results. |
| Need to adapt to the environment to survive. | No need to adapt to the environment, direct effect. |
| Direct colonisation and persistence in the gut. | Without colonisation, directly absorbed. |
| Instability after freeze-dried. | Highly stable without freeze-dried process. |
| Shorter shelf life. | Longer shelf-life up to 2 years at room temperature. |
| Induce pro-inflammatory response in hosts with inflamed gut. | Without any inflammatory response. |
| High risk to immuno-compromised patients. | No risk for immunity disorder patients. |
| Acquisition for virulence gene from pathogenic bacteria through horizontal gene transfer. | No virulence gene transfer. |
